![]() ![]() A light microscopic and immunohistochemical evaluation of scars. Kamath NV, Ormsby A, Bergfeld WF, House NS. Immunohistochemical localization of the proteoglycans decorin, biglycan and versican and transforming growth factor-b in human post-burn hypertrophic and mature scar. Scott PG, Dodd CM, Tredget EE, Ghahary A, Rahemtulla F. Effects of buflomedil and pentoxifylline on hamster skin-flap microcirculation: prediction of flap viability using orthogonal polarization spectral imaging. Mortality in anesthesia: a systematic review. Fluconazole plasma concentration measurement by liquid chromatography for drug monitoring of burn patients. Santos SR, Campos EV, Sanches C, Gomez DS, Ferreira MC. Topical tretinoin treatment alters the mechanical behavior of post-burn scarred skin by improving its distensibility and thus leads to improved quality of life for patients. However, tretinoin treatment did not significantly affect the density of collagen fibers, elastic fibers, or versican. ![]() Tretinoin treatment significantly lowered skin resistance and elastance, which is a result that indicates higher distensibility of the skin. The density of collagen fibers, elastic fibers, and versican were determined using immunohistochemical analysis. The resistance and elastance of these skin biopsies were measured using a mechanical oscillation analysis system. Skin biopsies were obtained initially and after one year of treatment. The objective of this prospective study was to examine the effects of treatment with 0.05% tretinoin for one year on the biomechanical behavior and histological changes undergone by facial skin with post-burn scarring.įifteen female patients who had suffered partial thickness burns with more than two years of evolution were selected. Topical treatment with tretinoin can improve the appearance and quality of the skin (i.e., texture, distensibility, color, and hydration). For the best results, you should avoid further skin damage when. After burn injuries, scarred skin lacks elasticity, especially in hypertrophic scars. Adapalene and benzoyl peroxide are commonly used to treat blemishes and acne scars. ![]()
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